Here you will find a series of online tutorials to help you identify what you see in your crystallization drop, and what do to about it. Is it a hit worth optimizing, or should you keep screening? What is the best way to optimize a hit? Finally, take the quiz to see how well you do on drop phenomena identification.
Beauty is only skin deep as the saying goes. The first thing you should learn is that the appearance (also referred to as the habit or morphology) of your crystal is NOT what is important.
Precipitates and crystals are relatively easy to recognize, but they are many other solid phases of protein that can occur in the drops. What do spherulites, oils, phase separation, and gels look like?